MCM4

MCM4
Identifiers
Aliases	MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21, minichromosome maintenance complex component 4, IMD54
External IDs	OMIM: 602638; MGI: 103199; HomoloGene: 40496; GeneCards: MCM4; OMA:MCM4 - orthologs
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	15,455,264 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow cells; ; human penis; ; stromal cell of endometrium; ; oocyte; ; appendix; ; trabecular bone; ; rectum; ; sperm; ; skin of abdomen;
	Top expressed in
	mandibular prominence; ; maxillary prominence; ; primitive streak; ; somite; ; external carotid artery; ; Paneth cell; ; abdominal wall; ; internal carotid artery; ; epiblast; ; ureter;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	single-stranded DNA binding; nucleotide binding; DNA helicase activity; DNA binding; protein binding; hydrolase activity; ATP binding; helicase activity; DNA replication origin binding;
Cellular component	MCM complex; membrane; nucleus; nucleoplasm;
Biological process	G1 phase; DNA replication; cell cycle; DNA replication initiation; DNA unwinding involved in DNA replication; G1/S transition of mitotic cell cycle; double-strand break repair via break-induced replication; pre-replicative complex assembly involved in nuclear cell cycle DNA replication; DNA strand elongation involved in DNA replication; mitotic DNA replication initiation;
	Sources:Amigo / QuickGO
Orthologs
	4173
	17217
	n/a
	ENSMUSG00000022673
	P33991
	P49717
	NM_005914; NM_182746
	NM_008565
	NP_005905; NP_877423
	NP_032591
	Wikidata
View/Edit Human	View/Edit Mouse

DNA replication licensing factor MCM4 is a protein that in humans is encoded by the MCM4 gene.^[4]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022673 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Musahl C, Schulte D, Burkhart R, Knippers R (August 1995). "A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins". Eur J Biochem. 230 (3): 1096–101. doi:10.1111/j.1432-1033.1995.tb20660.x. PMID 7601140.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000022673 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7601140-4] Musahl C, Schulte D, Burkhart R, Knippers R (August 1995). "A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins". Eur J Biochem. 230 (3): 1096–101. doi:10.1111/j.1432-1033.1995.tb20660.x. PMID 7601140.

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