MMP10

MMP10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Q3A, 3V96, 4ILW
Identifiers
Aliases	MMP10, SL-2, STMY2, matrix metallopeptidase 10
External IDs	OMIM: 185260; MGI: 97007; HomoloGene: 20546; GeneCards: MMP10; OMA:MMP10 - orthologs
EC number	3.4.24.22
Gene location (Human)
Chr.	Chromosome 11 (human)
End	102,780,628 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	7,510,241 bp
RNA expression pattern
	Top expressed in
	mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; palpebral conjunctiva; ; nasal epithelium; ; cartilage tissue; ; islet of Langerhans; ; epithelium of nasopharynx; ; stromal cell of endometrium; ; pancreatic epithelial cell; ; decidua;
	Top expressed in
	duodenum; ; jejunum; ; Paneth cell; ; integument; ; decidua; ; ileum; ; colon; ; ovary; ; muscle of leg; ; uterus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; peptidase activity; metalloendopeptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; serine-type endopeptidase activity;
Cellular component	extracellular region; extracellular space; extracellular matrix;
Biological process	collagen catabolic process; extracellular matrix disassembly; regulation of cell migration; proteolysis; response to hypoxia; extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	4319
	17384
	ENSG00000166670
	ENSMUSG00000047562
	P09238
	O55123
	NM_002425
	NM_019471
	NP_002416
	NP_062344
	Wikidata
View/Edit Human	View/Edit Mouse

Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166670 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047562 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988). "The collagenase gene family in humans consists of at least four members". The Biochemical Journal. 253 (1): 187–92. doi:10.1042/bj2530187. PMC 1149273. PMID 2844164.
^ Jung JY, Warter S, Rumpler Y (1990). "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization". Annales de Génétique. 33 (1): 21–3. PMID 2369069.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166670 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047562 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2844164-5] Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988). "The collagenase gene family in humans consists of at least four members". The Biochemical Journal. 253 (1): 187–92. doi:10.1042/bj2530187. PMC 1149273. PMID 2844164.

[pmid2369069-6] Jung JY, Warter S, Rumpler Y (1990). "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization". Annales de Génétique. 33 (1): 21–3. PMID 2369069.

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