MXI1

MXI1
Identifiers
Aliases	MXI1, MAD2, MXD2, MXI, bHLHc11, MAX interactor 1, dimerization protein
External IDs	OMIM: 600020; MGI: 97245; HomoloGene: 4351; GeneCards: MXI1; OMA:MXI1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	110,287,365 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	53,364,241 bp
RNA expression pattern
	Top expressed in
	optic nerve; ; Achilles tendon; ; corpus callosum; ; inferior ganglion of vagus nerve; ; trabecular bone; ; parotid gland; ; middle frontal gyrus; ; subthalamic nucleus; ; external globus pallidus; ; postcentral gyrus;
	Top expressed in
	blood; ; cerebellar vermis; ; molar; ; lobe of cerebellum; ; epithelium of small intestine; ; granulocyte; ; median eminence; ; olfactory epithelium; ; pontine nuclei; ; medial geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; protein dimerization activity; transcription corepressor activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleolus; nucleus; cytosol; RNA polymerase II transcription regulator complex;
Biological process	cytoplasmic sequestering of transcription factor; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of cell population proliferation; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4601
	17859
	ENSG00000119950
	ENSMUSG00000025025
	P50539
	P50540
	NM_130439; NM_001008541; NM_005962
NM_001008542; NM_001008543; NM_010847; NM_001360345; NM_001360346;
	NM_001360347; NM_001360348
	NP_001008541; NP_005953; NP_569157
NP_001008542; NP_001008543; NP_034977; NP_001347274; NP_001347275;
	NP_001347276; NP_001347277
	Wikidata
View/Edit Human	View/Edit Mouse

MAX-interacting protein 1 is a protein that in humans is encoded by the MXI1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119950 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025025 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wechsler DS, Hawkins AL, Li X, Jabs EW, Griffin CA, Dang CV (Nov 1994). "Localization of the human Mxi1 transcription factor gene (MXI1) to chromosome 10q24-q25". Genomics. 21 (3): 669–72. doi:10.1006/geno.1994.1336. PMID 7959753.
^ "Entrez Gene: MXI1 MAX interactor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119950 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025025 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7959753-5] Wechsler DS, Hawkins AL, Li X, Jabs EW, Griffin CA, Dang CV (Nov 1994). "Localization of the human Mxi1 transcription factor gene (MXI1) to chromosome 10q24-q25". Genomics. 21 (3): 669–72. doi:10.1006/geno.1994.1336. PMID 7959753.

[entrez-6] "Entrez Gene: MXI1 MAX interactor 1".

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