Main Line (Pennsylvania Railroad)

For the suburban area west of Philadelphia, see Philadelphia Main Line. For other meanings, see Main Line (disambiguation).
Crossing of the Alleghany, Pennsylvania Railroad, 1853 print

The Main Line of the Pennsylvania Railroad was a rail line in Pennsylvania connecting Philadelphia with Pittsburgh via Harrisburg. The rail line was split into two rail lines, and now all of its right-of-way is a cross-state corridor, composed of Amtrak's Philadelphia to Harrisburg Main Line (including SEPTA's Paoli/Thorndale Line service) and the Norfolk Southern Railway's Pittsburgh Line.