Manuel Elkin Patarroyo

In this Spanish name, the first or paternal surname is Patarroyo and the second or maternal family name is Murillo.
Manuel Elkin Patarroyo
Born
Manuel Elkin Patarroyo Murillo

(1946-11-03) November 3, 1946 (age 77)
Ataco, Tolima, Colombia
EducationNational University of Colombia (MD)
Known forSPf66 Malaria vaccine
Medical career
ProfessionPhysician-scientist
Institutions
Sub-specialtiesPathologist
ResearchImmunology
Awards

Manuel Elkin Patarroyo Murillo (born November 3, 1946)[1] is a Colombian Professor of Pathology and Immunology who made the world's first attempt to create a synthetic vaccine against the protozoal parasite Plasmodium falciparum, the cause of severe malaria,[2] and responsible for the death of ~1.5 million people per year in tropical and subtropical regions, including parts of the Americas, Asia, and Africa.

The vaccine candidate, first developed in 1987 in Colombia, was evaluated in clinical trials carried out by the WHO in Gambia, Tanzania and Thailand, and had mixed results.[3] In 2009, a comprehensive Cochrane review assessed the SPf66 as being not efficacious in Africa and Asia, and as having a low but statistically significant efficacy of 28% in South America.[4] Researchers and vaccine developers have been working on many approaches to bring forward the availability of a malaria vaccine."[5] More research and clinical trials are required for a universal vaccine to be implemented.

Patarroyo is a recipient of the TWAS Prize (1998).[6]

  1. ^ Fundación Príncipe de Asturias. Manuel Elkin Patarroyo Archived 2008-05-13 at the Wayback Machine (Spanish). Premiados, Investigación Científica y Técnica, 1994.
  2. ^ Holloway, M. (1996) Profile: Manuel Elkin Patarroyo – The Man Who Would Conquer Malaria, Scientific American 275(6), 52-56.
  3. ^ - Susan Aldridge, Magic Molecules: How Drugs Work (Cambridge University Press, 1998), p. 89
  4. ^ - Graves, P. M. and Gelband, H. (2009) Vaccines for preventing malaria (SPf66) (Review), The Cochrane Library 2009, (2), pp.1-38. Archived 2011-07-20 at the Wayback Machine
  5. ^ - WHO (2010) Tables of Malaria Vaccine Projects Globally (Updated December 2010), Initiative for Vaccine Research.
  6. ^ "Prizes and Awards". The World Academy of Sciences. 2016.