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| Manuel of Castile | |
|---|---|
 House of Manuel of Villena coat of arms. | |
| Lord of Villena | |
| Reign | 1252 – 1283 |
| Successor | Juan Manuel, Prince of Villena |
| Born | 1234 Carrión de los Condes |
| Died | 25 December 1283 (aged 48–49) Peñafiel, Spain |
| Burial | Monastery of Uclés |
| Spouse | Constance of Aragon Beatrice of Savoy |
| Issue | Violante Manuel Juan Manuel, Prince of Villena |
| House | Castilian House of Ivrea |
| Father | Ferdinand III of Castile |
| Mother | Elisabeth of Hohenstaufen |
Manuel of Castile (1234 – 25 December 1283, The first Lord of Villena and Peñafiel, Cuéllar, and Escalona, was an Infante, son of Ferdinand III of Castile and his wife Elisabeth of Hohenstaufen.