Margaret More or Moore may refer to:
- Margaret Roper (1505–1544), née More, English writer and translator, daughter of Sir Thomas More
- Margaret Clement (1508–1570), née Giggs, English noblewoman, adopted daughter of Sir Thomas More
- Kate Barry (1752–1823), or Margaret Barry, née Moore, American Revolutionary War heroine
- Maggie Moore (1851–1926), American-Australian actress
- Margaret Hodges (1911–2005), née Moore, American author
- Margaret Moore, Canadian author
- Margaret Ann Moore, Canadian-American author and executive coach
- Margaret More (composer) (1903–1966), Welsh composer, daughter-in-law of Sir Granville Bantock
- Margaret Moore (academic), Canadian political theorist, academic and scholar