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| Margaret of Sicily | |
|---|---|
 Margaret | |
| Born | 1 December 1241 Foggia, Kingdom of Sicily |
| Died | 8 August 1270 Frankfurt-am-Main, Holy Roman Empire |
| Spouse | Albert "the Degenerate" |
| Issue | Henry Frederick Theodoric Margaret Agnes of Meissen |
| House | House of Hohenstaufen |
| Father | Frederick II, Holy Roman Emperor |
| Mother | Isabella of England |
Margaret of Sicily (also called Margaret of Hohenstaufen or Margaret of Germany) (1 December 1241, in Foggia – 8 August 1270, in Frankfurt-am-Main) was a Princess of Sicily and Germany, and a member of the House of Hohenstaufen. By marriage she was Landgravine of Thuringia and Countess Palatine of Saxony (German: Landgräfin von Thüringen und Pfalzgräfin von Sachsen).
She was the daughter of Frederick II, Holy Roman Emperor, King of Sicily and Germany, by his third wife, Isabella of England. Her paternal grandparents were Henry VI, Holy Roman Emperor and Constance of Sicily. Her maternal grandparents were John of England and Isabella of Angoulême.