| Margherita Farnese | |
|---|---|
 | |
| Hereditary Princess of Mantua | |
| Tenure | 2 March 1581 – 26 May 1583 |
| Born | 7 November 1567 Parma, Duchy of Parma and Piacenza |
| Died | 13 April 1643 (aged 75) Monastery of Sant'Alessandro, Parma, Duchy of Parma and Piacenza |
| Burial | |
| Spouse | |
| Father | Alexander Farnese, Duke of Parma |
| Mother | Infanta Maria of Portugal |
Margherita Farnese (7 November 1567 – 13 April 1643), was an Italian noblewoman member of the House of Farnese and by marriage Hereditary Princess of Mantua between 1581–1583.
Her marriage to Vincenzo Gonzaga, Hereditary Prince of Mantua was annulled after two years due to Margherita's inability to consummate due to deformity of the genitals. After her divorce, the princess took monastic vows with the name of Sister Maura Lucenia and became abbess of the monastery of Sant'Alessandro, Parma.