| Listed race | |
| Location | Suffolk Downs East Boston, Massachusetts, USA |
|---|---|
| Inaugurated | 1935 |
| Race type | Thoroughbred - Flat racing |
| Race information | |
| Distance | 5.5f - 8.32f |
| Surface | Dirt |
| Track | Left-handed |
| Qualification | Two-year-olds |
The Mayflower Stakes was one of the premiere juvenile stakes in New England. Run at Suffolk Downs, the Mayflower was held from Suffolk's inauguration in 1935 to 1988, when Suffolk was purchased from the Ogden Corporation. Run from 5+1⁄2 furlongs to about 8+5⁄16 furlongs, the event was never graded.
Notable horses to race in the Mayflower Stakes were Alsab, Pavot, Quadrangle, Sword Dancer, Timely Writer, and Seabiscuit.
Three fillies have won an edition of this race.