| Mediastinal fibrosis | |
|---|---|
 | |
| Mediastinal fibrosis is inherited in an autosomal recessive manner | |
| Specialty | Pulmonology |
| Causes | histoplasmosis |
| Treatment | glucocorticoids or immunosuppressants[1] |
Mediastinal fibrosis is characterized by invasive, calcified fibrosis centered on lymph nodes that block major vessels and airways. In Europe, this disease is exceptionally rare. More cases are seen in USA where the disease may often be associated with histoplasmosis.[2][3]
- ^ Rossi, Giovanni M.; Emmi, Giacomo; Corradi, Domenico; Urban, Maria L.; Maritati, Federica; Landini, Federica; Galli, Paola; Palmisano, Alessandra; Vaglio, Augusto (June 2017). "Idiopathic Mediastinal Fibrosis: a Systemic Immune-Mediated Disorder. A Case Series and a Review of the Literature". Clinical Reviews in Allergy & Immunology. 52 (3): 446–459. doi:10.1007/s12016-016-8584-1. PMID 27553003. S2CID 46747661.
- ^ Davis AM, Pierson RN, Loyd JE (2001). "Mediastinal fibrosis". Seminars in Respiratory Infections. 16 (2): 119–30. doi:10.1053/srin.2001.24242. PMID 11521244.
- ^ Mitchell IM, Saunders NR, Maher O, Lennox SC, Walker DR (1986). "Surgical treatment of idiopathic mediastinal fibrosis: report of five cases". Thorax. 41 (3): 210–4. doi:10.1136/thx.41.3.210. PMC 460296. PMID 3715778.