Melanocortin 5 receptor

MC5R
Identifiers
AliasesMC5R, MC2, Melanocortin 5 receptor
External IDsOMIM: 600042; MGI: 99420; HomoloGene: 4321; GeneCards: MC5R; OMA:MC5R - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005913

NM_013596

RefSeq (protein)

NP_005904

NP_038624

Location (UCSC)Chr 18: 13.82 – 13.83 MbChr 18: 68.47 – 68.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Melanocortin 5 receptor (MC5R) is a protein that in humans is encoded by the MC5R gene.[5][6] It is located on the chromosome 18 in the human genome.[6] When the MC5R was disrupted in transgenic mice, it induced disruption of their exocrine glands and resulted in decreased production of sebum.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176136Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000007480Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chhajlani V, Muceniece R, Wikberg JE (September 1993). "Molecular cloning of a novel human melanocortin receptor". Biochemical and Biophysical Research Communications. 195 (2): 866–73. doi:10.1006/bbrc.1993.2125. PMID 8396929.
  6. ^ a b "Entrez Gene: MC5R melanocortin 5 receptor".
  7. ^ Thiboutot D, Sivarajah A, Gilliland K, Cong Z, Clawson G (October 2000). "The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells". The Journal of Investigative Dermatology. 115 (4): 614–9. doi:10.1046/j.1523-1747.2000.00094.x. PMID 10998132.