Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene.[5][6] mGluR2 is a G protein-coupled receptor (GPCR) that couples with the Gi alpha subunit.[7] The receptor functions as an autoreceptor for glutamate, that upon activation, inhibits the emptying of vesicular contents at the presynaptic terminal of glutamatergic neurons.
- ^ a b c GRCh38: Ensembl release 89: ENSG00000164082 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023192 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Flor PJ, Lindauer K, Püttner I, Rüegg D, Lukic S, Knöpfel T, Kuhn R (April 1995). "Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 2". The European Journal of Neuroscience. 7 (4): 622–9. doi:10.1111/j.1460-9568.1995.tb00666.x. PMID 7620613. S2CID 30186477.
- ^ "Entrez Gene: GRM2 glutamate receptor, metabotropic 2".
- ^ Kammermeier PJ, Davis MI, Ikeda SR (January 2003). "Specificity of metabotropic glutamate receptor 2 coupling to G proteins". Molecular Pharmacology. 63 (1): 183–91. doi:10.1124/mol.63.1.183. PMID 12488551. S2CID 26178233.