Metabotropic glutamate receptor 6

GRM6
Identifiers
Aliases	GRM6, CSNB1B, GPRC1F, MGLUR6, mGlu6, glutamate metabotropic receptor 6
External IDs	OMIM: 604096; MGI: 1351343; HomoloGene: 20232; GeneCards: GRM6; OMA:GRM6 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	178,996,206 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	50,757,035 bp
RNA expression pattern
	Top expressed in
	testicle; ; pancreatic ductal cell; ; tibialis anterior muscle; ; cerebellar hemisphere; ; ganglionic eminence; ; right hemisphere of cerebellum; ; anterior pituitary; ; deltoid muscle; ; hypothalamus; ; Ventricular system of neuraxis;
	Top expressed in
	neural layer of retina; ; embryo; ; epiblast; ; spleen; ; thymus; ; bone marrow; ; lens; ; islet of Langerhans;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glutamate receptor activity; G protein-coupled receptor activity; protein homodimerization activity; signal transducer activity; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; protein binding;
Cellular component	integral component of membrane; Golgi apparatus; cell projection; endoplasmic reticulum membrane; membrane; Golgi membrane; plasma membrane; integral component of plasma membrane; dendrite; endoplasmic reticulum; presynaptic membrane; new growing cell tip;
Biological process	G protein-coupled glutamate receptor signaling pathway; detection of visible light; locomotory behavior; response to stimulus; sensory perception of light stimulus; detection of light stimulus involved in visual perception; positive regulation of calcium ion import; retina development in camera-type eye; signal transduction; visual perception; chemical synaptic transmission; regulation of synaptic transmission, glutamatergic; adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2916
	108072
	ENSG00000113262
	ENSMUSG00000000617
	O15303
	Q5NCH9
	NM_000843
	NM_173372
	NP_000834
	NP_775548
	Wikidata
View/Edit Human	View/Edit Mouse

Glutamate receptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113262 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000000617 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GRM6 glutamate receptor, metabotropic 6".
^ Hashimoto T, Inazawa J, Okamoto N, Tagawa Y, Bessho Y, Honda Y, Nakanishi S (June 1997). "The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6". Eur. J. Neurosci. 9 (6): 1226–35. doi:10.1111/j.1460-9568.1997.tb01477.x. PMID 9215706. S2CID 25387864.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113262 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000000617 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GRM6 glutamate receptor, metabotropic 6".

[pmid9215706-6] Hashimoto T, Inazawa J, Okamoto N, Tagawa Y, Bessho Y, Honda Y, Nakanishi S (June 1997). "The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6". Eur. J. Neurosci. 9 (6): 1226–35. doi:10.1111/j.1460-9568.1997.tb01477.x. PMID 9215706. S2CID 25387864.

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