Metastasis suppressor

A metastasis suppressor is a protein that acts to slow or prevent metastases (secondary tumors) from spreading in the body of an organism with cancer. Metastasis is one of the most lethal cancer processes. This process is responsible for about ninety percent of human cancer deaths.[1][2] Proteins that act to slow or prevent metastases are different from those that act to suppress tumor growth. Genes for about a dozen such proteins are known in humans and other animals.[3]

  1. ^ Olle, David (September 9, 2009). "Metastasis Suppressors". Suite 101. {{cite web}}: Missing or empty |url= (help)[self-published source?]
  2. ^ Gkountela, Sofia; Aceto, Nicola (2016-07-26). "Stem-like features of cancer cells on their way to metastasis". Biology Direct. 11: 33. doi:10.1186/s13062-016-0135-4. ISSN 1745-6150. PMC 4960876. PMID 27457474.
  3. ^ Sobel, Mark E. (1990). "Metastasis Suppressor Genes". Journal of the National Cancer Institute. 82 (4): 267–76. doi:10.1093/jnci/82.4.267. PMID 2405170.