| methenyltetrahydrofolate cyclohydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Methenyltetrahydrofolate cyclohydrolase dimer, Human | |||||||||
| Identifiers | |||||||||
| EC no. | 3.5.4.9 | ||||||||
| CAS no. | 9027-97-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) is an enzyme that catalyzes the chemical reaction
- 5,10-methenyltetrahydrofolate + H2O 10-formyltetrahydrofolate
Thus, the two substrates of this enzyme are 5,10-methenyltetrahydrofolate and H2O, whereas its product is 10-formyltetrahydrofolate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines.
This enzyme participates in glyoxylate and dicarboxylate metabolism and one carbon pool by folate.