Methyl fluoroacetate

Methyl fluoroacetate

  Carbon, C
  Hydrogen, H
  Oxygen, O
  Fluorine, F
Names
Preferred IUPAC name
Methyl fluoroacetate
Other names
  • AF-1
  • MFA
  • T-1202
  • TL-551
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.563 Edit this at Wikidata
EC Number
  • 207-218-7
UNII
  • InChI=1S/C3H5FO2/c1-6-3(5)2-4/h2H2,1H3
    Key: RJBYSQHLLIHSLT-UHFFFAOYSA-N
  • COC(=O)CF
Properties
FCH2CO2CH3
Molar mass 92.069 g·mol−1
Appearance Colorless liquid
Odor Odorless or faint fruity
Melting point −40 °C (−40 °F; 233 K)
Boiling point 104 °C (219 °F; 377 K)
117 g/L at 25 °C
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
GHS labelling:
GHS02: FlammableGHS06: ToxicGHS07: Exclamation markGHS09: Environmental hazard
Danger
H226, H300, H315, H319, H335, H400
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P370+P378, P391, P403+P233, P403+P235, P405, P501
Flash point −32 °C (−26 °F; 241 K)
Lethal dose or concentration (LD, LC):
6 mg/kg (mice)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Methyl fluoroacetate (MFA) is an organic compound with the chemical formula FCH2CO2CH3. It is the extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room temperature. It is used as a laboratory chemical and as a rodenticide. Because of its extreme toxicity, MFA was studied for potential use as a chemical weapon.[1]

The general population is not likely to be exposed to methyl fluoroacetate. People who use MFA for work, however, can breathe in or have direct skin contact with the substance.[2]

  1. ^ Gribble, Gordon W. (July 1973). "Fluoroacetate toxicity" (PDF). Journal of Chemical Education. 50 (7): 460–2. Bibcode:1973JChEd..50..460G. doi:10.1021/ed050p460. PMID 4711243.
  2. ^ National Center for Biotechnology Information. PubChem Database. Methyl fluoroacetate, CID=9959, https://pubchem.ncbi.nlm.nih.gov/compound/Methyl-fluoroacetate (accessed on Mar. 20, 2020)