Michael J. Sailor

Michael J. Sailor
NationalityAmerican
Alma materHarvey Mudd College (B.S., 1983)
Northwestern University (M.S., Ph.D. 1988)
Known forPorous silicon nanotechnology
Scientific career
FieldsNanotechnology, Porous silicon, Biomaterials
InstitutionsUniversity of California, San Diego (1990–)

Michael J. Sailor is a nanotechnology researcher and professor at the University of California, San Diego.[1] Sailor is best known for his research on porous silicon, a nanostructured material that is prepared by electrochemical corrosion of crystalline silicon wafers.[2]

He pioneered the development of label-free biosensors from thin optical films of porous silicon.[3] He prepared the first microparticles and nanoparticles of porous silicon,[4] and harnessed the intrinsic photoluminescence of these formulations for in vitro and in vivo imaging applications.[5] He was the first to demonstrate time-gated luminescence imaging with these nanoparticles,[6] important because time-gating suppresses tissue autofluorescence that often compromises the fidelity of fluorescence images of biological tissues. He also adapted the concept of "Smart Dust" to the field of nanotechnology: the idea that microscopic particles can be manufactured with optical, chemical, and mechanical properties that can perform sensing, signaling, and motive functions.[7][8][9][10]

  1. ^ "Michael J. Sailor Biographical". UCSD Sailor Research Group. University of California, San Diego.
  2. ^ Sailor, Michael J. (2012). Porous silicon in practice preparation, characterization and applications. Weinheim: Wiley-VCH. p. 249. ISBN 9783527313785.
  3. ^ Lin, V.S.Y.; Motesharei, K.; Sailor, M. J.; Ghadiri, M. R. (31 October 1997). "A Porous Silicon-Based Optical Interferometric Biosensor". Science. 278 (5339): 840–843. Bibcode:1997Sci...278..840L. doi:10.1126/science.278.5339.840. PMID 9346478.
  4. ^ Heinrich, J.L.; Curtis, C.L.; Credo, G.M.; Kavanagh, K.L.; Sailor, M.J. (3 January 1992). "Luminescent colloidal Si suspensions from porous Si". Science. 255 (5040): 66–68. doi:10.1126/science.255.5040.66. PMID 17739915. S2CID 19694068.
  5. ^ Park, J.H.; Gu, L.; Rouslahti, E.; Bhatia, S.N.; Sailor, M.J. (22 February 2009). "Biodegradable luminescent porous silicon nanoparticles for in vivo applications". Nature Materials. 8 (4): 331–336. Bibcode:2009NatMa...8..331P. doi:10.1038/nmat2398. PMC 3058936. PMID 19234444.
  6. ^ Gu, L.; Hall, D.J.; Qin, Z.; Anglin, E.; Joo, J.; Mooney, D.J.; Howell, S.B.; Sailor, M.J. (12 August 2013). "In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles". Nature Communications. 4: 2326. Bibcode:2013NatCo...4.2326G. doi:10.1038/ncomms3326. PMC 4154512. PMID 23933660.
  7. ^ Sailor, M.J.; Link, J.R. (10 Feb 2005). "Smart Dust: nanostructured devices in a grain of sand". Chemical Communications (11): 1375–1383. doi:10.1039/b417554a. PMID 15756310.
  8. ^ Dovree, J.R.; Derfus, A.M.; Bhatia, S.N.; Sailor, M.J. (7 November 2004). "Manipulation of liquid droplets using amphiphilic, magnetic 1-D photonic crystal chaperones". Nature Materials. 3 (12): 896–899. doi:10.1038/nmat1253. PMID 15531887. S2CID 8177935.
  9. ^ Link, J.R.; Sailor, M.J. (June 19, 2003). "Smart Dust: Self-assembling, self-orienting photonic crystals of porous Si". Proceedings of the National Academy of Sciences. 100 (19): 10607–10610. Bibcode:2003PNAS..10010607L. doi:10.1073/pnas.1233824100. PMC 196851. PMID 12947036.
  10. ^ Schmedake, T.A.; Cunin, F.; Link, J.R.; Sailor, M.J. (16 September 2002). "Standoff detection of chemicals using porous silicon 'Smart Dust' particles". Advanced Materials. 14 (18): 1270–1272. doi:10.1002/1521-4095(20020916)14:18<1270::AID-ADMA1270>3.0.CO;2-R.