Michael Knox may refer to:
- Michael D. Knox (born 1946), American psychologist and professor
- Michael Knox (software businessman) (1961–2009), American software businessman and expert
- Michael Knox (record producer), American record producer
- Mike Knox (born 1978), American wrestler
- Mike Knox (politician), Houston politician
- Mickey Knox (1921–2013), actor who fell victim to the Hollywood blacklist
This disambiguation page lists articles about people with the same name.
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