Michael Merzenich

Michael M. Merzenich
Born
Michael Matthias Merzenich

1942 (age 81–82)
EducationUniversity of Portland (SB)
Johns Hopkins Medical School (PhD)
University of Wisconsin
Known forBrain plasticity research[1]
Medical career
ProfessionNeuroscience
InstitutionsUniversity of California, San Francisco
ResearchBasic and clinical sciences of hearing
AwardsNational Academy of Sciences, Institute of Medicine, Kavli Prize, Russ Prize, Karl Spencer Lashley Award

Michael Matthias Merzenich[2] (/ˈmɜːrzənɪk/ MURR-zə-nik;[3] born 1942 in Lebanon, Oregon) is an American neuroscientist and professor emeritus at the University of California, San Francisco. He took the sensory cortex maps developed by his predecessors (Archie Tunturi, Clinton Woolsey, Vernon Mountcastle, Wade Marshall, and Philip Bard) and refined them using dense micro-electrode mapping techniques. Using this, he definitively showed there to be multiple somatotopic maps of the body in the postcentral sulcus,[4][5] and multiple tonotopic maps of the acoustic inputs in the superior temporal plane.[6]

He led the cochlear implant team at UCSF,[1][7] which transferred its technology to Advanced Bionics,[8] and their version is the Clarion cochlear implant.[9] He collaborated with Bill Jenkins and Gregg Recanzone to demonstrate sensory maps are labile into adulthood in animals performing operant sensory tasks.[10][11][12] He collaborated with Paula Tallal, Bill Jenkins, and Steve Miller to form the company Scientific Learning.[1][13] This was based on Fast ForWord software they co-invented that produces improvements in children's language skills that has been related to the magnitude of their temporal processing impairments prior to training,[14] though the program's effectiveness is disputed.[15][16]

Merzenich was director and Chief Scientific Officer of Scientific Learning between November 1996 and January 2003. Merzenich took two sabbaticals from UCSF, in 1997 and 2004. In 1997 he led research teams at Scientific Learning Corporation, and in 2004 at Posit Science Corporation.[17] Currently, Merzenich's second company, Posit Science Corporation, is working on a broad range of behavioral therapies. Their lead product is a brain-training application called BrainHQ (TM).[18] Merzenich is Chief Scientific Officer, and on the Board of Directors, at Posit Science.[17]

  1. ^ a b c "Michael M. Merzenich, Ph.D. – Posit Science Corporation University of California at San Francisco". Posit Science. 2014. Retrieved 2009-01-02.
  2. ^ "Doctors of Philosophy in The School of Medicine with titles of dissertations". Conferring of Degrees at the close of the ninety-second academic year (PDF). Baltimore, Maryland: The Johns Hopkins University. 11 June 1968. p. 28. Retrieved 4 November 2020.
  3. ^ "Dr. Michael Merzenich: Neuromodulation and Neuroplasticity in Reading Related Brain Processes -1". YouTube. Archived from the original on 2021-12-19. Retrieved 21 June 2020.
  4. ^ Paul, R.L.; Merzenich, M. & H. Goodman (1972). "Representation of slowly and rapidly adapting cutaneous mechanoreceptors of the hand in Brodmann's areas 3 and 1 of Macaca mulatta". Brain Research. 36 (2): 229–49. doi:10.1016/0006-8993(72)90732-9. PMID 4621596.
  5. ^ Merzenich, M.M.; Kaas, M., M. Sur and C.S. Lin (1978). "Double representation of the body surface within cytoarchitectonic areas 3b and 2 in Sl in the owl monkey (Aotus trivirgatus)" (PDF). J. Comp. Neurol. 181 (Listed in the bibliography for Abstract 11:965): 41–73. doi:10.1002/cne.901810104. PMID 98537. S2CID 12388135.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ Brain Research 50:275-96 1973
  7. ^ Med. Biol. Eng. Computing 21:241–54 1983
  8. ^ "BionicEar.com – Harmony Cochlear Implant by Advanced Bionics". Advanced Bionics. 2009. Retrieved 2009-01-02.
  9. ^ "BionicEar.com – Harmony Cochlear Implant by Advanced Bionics". Advanced Bionics. 2009. Retrieved 2009-01-02.
  10. ^ Jenkins, W.M.; Merzenich, M.M., M. T. Ochs, T. Allard and E. Guic-Robles (1990). "Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation". J Neurophysiol. 63 (1): 82–104. doi:10.1152/jn.1990.63.1.82. PMID 2299388. S2CID 3954439.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  11. ^ J. Neurophysiol. 67:1031–56 1992
  12. ^ J. Neurosci. 13:87–103 1993
  13. ^ "Michael M. Merzenich | Scientific Learning". Scientific Learning Corporation. 1997–2009. Archived from the original on 2009-01-08. Retrieved 2009-01-02.
  14. ^ Science 271:77–84 1996
  15. ^ Strong GK, Torgerson CJ, Torgerson D, Hulme C (March 2011). "A systematic meta-analytic review of evidence for the effectiveness of the 'Fast ForWord' language intervention program". J Child Psychol Psychiatry. 52 (3): 224–35. doi:10.1111/j.1469-7610.2010.02329.x. PMC 3061204. PMID 20950285.
  16. ^ Simons, DJ; Boot, WR; Charness, N; Gathercole, SE; Chabris, CF; Hambrick, DZ; Stine-Morrow, EA (October 2016). "Do "Brain-Training" Programs Work?". Psychological Science in the Public Interest. 17 (3): 103–86. doi:10.1177/1529100616661983. PMID 27697851.
  17. ^ a b Cite error: The named reference Forbes was invoked but never defined (see the help page).
  18. ^ BrainHQ