Michele Di Giesi (4 September 1927 – 20 November 1983) was an Italian politician. He served in the cabinet of Prime Minister Forlani (1980–1981) and Spadolini (1981–1982). He served in the Chamber of Deputies of Italy in Legislature VI (1972–1976), Legislature VII (1976–1979), Legislature VIII (1979–1983) and Legislature IX.
An exponent of the Italian Democratic Socialist Party, Di Giesi has been several times Minister of the Italian Republic.