Miso is a traditional Japanese seasoning.
MISO or Miso may also refer to:
- MISO, short for Multiple Inputs, Single Output in system analysis
- Master Input, Slave Output, a data line in the Serial Peripheral Interface Bus
- Military information support operations, the U.S. military term for the function formally known as Psychological Operations
- Midcontinent Independent System Operator, formerly known as Midwest Independent Transmission System Operator
- Misophonia, a neurological and hearing disorder characterized by fear or anxiety over certain sounds