Look up Mississippian in Wiktionary, the free dictionary.
Mississippian may refer to:
- Mississippian (geology), a subperiod of the Carboniferous period in the geologic timescale, roughly 360 to 325 million years ago
- Mississippian culture, a culture of Native American mound-builders from 900 to 1500 AD
- Mississippian Railway, a short line railroad
- A native of Mississippi