Mr. Freeze is the name of two supervillains appearing in American comic books published by DC Comics. Created by writer Dave Wood and artists Sheldon Moldoff and Bob Kane, the character initially debuted in Batman #121 (February 1959) as Mr. Zero, a mad scientist with an unknown birth name who, after a physiology-altering mishap, becomes an ice-themed criminal typically armed with freezing weapons and an adversary of the superhero Batman forced to live in sub-zero temperatures and wear a special "cryo-suit" for survival. He was later renamed "Mr. Freeze" after the version featured in the 1966 Batman television series.
In 1992, Mr. Freeze was reinvented as a tragic villain by writer Paul Dini, producer Bruce Timm, and artist Mike Mignola for Batman: The Animated Series, which portrayed Dr. Victor Fries, PhD (pronounced "freeze") as a scientist in Gotham City who suffers a lab accident while trying to cryogenically preserve his terminally ill wife, Nora. He turns to crime to fund his research in his obsessive quest to cure Nora by any means necessary, which brings him into conflict with Batman. The animated revamped depiction of Mr. Freeze received widespread acclaim and redefined the character, providing such a burst in his popularity that DC Comics retroactively integrated the origin story conceived by Dini into the mainstream comic book continuity, and adapted it for almost every incarnation of the Batman franchise since.
As one of Batman's most enduring enemies belonging to the collective of adversaries that make up his rogues gallery, Mr. Freeze has been adapted in various media incarnations. He has been portrayed in film by Arnold Schwarzenegger in Batman & Robin (1997), and in television by George Sanders, Otto Preminger, and Eli Wallach in the 1966 Batman series, and Nathan Darrow in Gotham. Michael Ansara, Clancy Brown, Maurice LaMarche, and others have provided the character's voice in animation and video games.