Murphy Roths large

Murphy Roths large (MRL/MpJ) is a strain of laboratory mouse developed in 1999 at The Wistar Institute in Philadelphia, Pennsylvania.[1] Originally bred for autoimmune disease research, it was discovered to have remarkable tissue regeneration abilities.[2][3][4]

  1. ^ Clark, Lise Desquenne; Clark, Robert K.; Heber-Katz, Ellen (July 1998). "A New Murine Model for Mammalian Wound Repair and Regeneration". Clinical Immunology and Immunopathology. 88 (1): 35–45. doi:10.1006/clin.1998.4519. ISSN 0090-1229. PMID 9683548. S2CID 3734804.
  2. ^ Heber-Katz, E.; Leferovich, J. M.; Bedelbaeva, K.; Gourevitch, D. (2004). "Spallanzani's Mouse: A Model of Restoration and Regeneration". Regeneration: Stem Cells and Beyond. Current Topics in Microbiology and Immunology. Vol. 280. pp. 165–89. doi:10.1007/978-3-642-18846-6_5. ISBN 978-3-642-62321-9. PMID 14594211.
  3. ^ Morelle, Rebecca (11 April 2006). "Mouse sheds light on regeneration". BBC News.
  4. ^ Carswell, Lindsay (18 April 2006). "Self-healing Mice". ScienCentral News. Archived from the original on 20 October 2008.