The music for the 2018 action-adventure game Red Dead Redemption 2, developed and published by Rockstar Games, consists of an original score composed by musician Woody Jackson and an original soundtrack produced by Daniel Lanois. The soundtrack album was released digitally in July 2019, consisting of vocal tracks with artists such as Willie Nelson, Rhiannon Giddens, and Josh Homme. The score album was released in August 2019, mostly consisting of Jackson's original work and collaborations with artists such as Colin Stetson, Senyawa, and Arca. An additional extended play, The Housebuilding EP, was released in February 2021, consisting of original songs by David Ferguson and Matt Sweeney. Two singles of music from the game have also been released: "Unshaken" by D'Angelo in January 2019, later released as part of the original soundtrack; and "Letter from Bluewater Man" by Christone "Kingfish" Ingram in August 2021, as part of an update for Red Dead Online.
Red Dead Redemption 2 has three different types of score: narrative, which is heard during the missions in the game's story; interactive, when the player is roaming the open world or in multiplayer; and environmental, which includes campfire singing songs or a character playing music in the world. The game's music regularly reacts according to the player's decisions in the world. Jackson composed roughly 60 hours of music for the game, though not every track made the final product. He purchased several instruments from the Wrecking Crew that were featured on classic cowboy films. Lanois was chosen to produce all of the game's vocal tracks for consistency and to complement Jackson's score. In total, over 110 musicians worked on the music for the game.
Critical reception to the soundtracks was positive, as reviewers felt that the music connected appropriately with the gameplay. In particular, critics felt that the minimalist approach of the score's composition matched the gameplay, genre, and time, and the vocal tracks were praised for their impactfulness. The game's music was nominated for numerous awards. Several tracks became popular and spawned cover versions and live performances.