A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis,[2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental and clinical sources. 2,042 have been completely sequenced.[3] Mycobacteriophages have served as examples of viral lysogeny and of the divergent morphology and genetic arrangement characteristic of many phage types.[4]
All mycobacteriophages found thus far have had double-stranded DNA genomes and have been classified by their structure and appearance into siphoviridae or myoviridae.[5]
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- ^ "Mycobacteriophage Database". Phagesdb.org. Retrieved 4 September 2017.
- ^ Hatfull GF (13 October 2010). "Mycobacteriophages: genes and genomes". Annual Review of Microbiology. 64 (1): 331–356. doi:10.1146/annurev.micro.112408.134233. PMID 20528690.
- ^ Pope WH, Jacobs-Sera D, Russell DA, Peebles CL, Al-Atrache Z, Alcoser TA, et al. (January 2011). "Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution". PLOS ONE. 6 (1): e16329. Bibcode:2011PLoSO...616329P. doi:10.1371/journal.pone.0016329. PMC 3029335. PMID 21298013.