Mycobacteroides

Mycobacteroides
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Mycobacteriales
Family: Mycobacteriaceae
Genus: Mycobacteroides
Gupta et al. 2018[1]
Type species
Mycobacteroides abscessus
(Moore and Frerichs 1953) Gupta et al. 2018
Species[2]
Synonyms[3]
  • M. chelonae–M. abscessus group (MCAG)
  • Mycobacterium chelonae–abscessus complex (MCAC)

Mycobacteroides is a genus of Gram-Positive rod-shaped bacteria in the family Mycobacteriaceae from the order Mycobacteriales.[1]

Members of Mycobacteroides were demarcated from the larger genus Mycobacterium in 2018 by Gupta et al. based on evidence from various phylogenetic trees constructed based on conserved genome sequences, comparative genomic analyses and average amino acid identity values.[1] In addition to this genus, the study proposed the division of Mycobacterium into a total of five distinct genera, which was met with some resistance by some of the scientific community. The resistance was based on the grounds that Mycobacterium contains some clinically relevant species and name changes might cause confusion among clinicians and other researchers.[4]

In 2020, Yamada et al. analyzed the fundamental morphological properties of the new genera, including the cell diameter, cell length, cell perimeter, cell circularity and aspect ratio, and determined that there were significant differences between the five genera, thus supporting the new division.[5]

The name Mycobacteroides is derived from the Latin noun Mycobacterium (referring to the bacterial genus) and the Latin suffix "-oides" (translates to "resembling"). Together the name refers to a genus resembling Mycobacterium.[1]

  1. ^ a b c d Gupta, Radhey S.; Lo, Brian; Son, Jeen (2018-02-13). "Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera". Frontiers in Microbiology. 9: 67. doi:10.3389/fmicb.2018.00067. ISSN 1664-302X. PMC 5819568. PMID 29497402.
  2. ^ Euzéby JP, Parte AC. "Mycobacteroides". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved June 25, 2022.
  3. ^ Richardson, E. T.; Samson, D.; Banaei, N. (May 2009). "Rapid Identification of Mycobacterium tuberculosis and nontuberculous mycobacteria by multiplex, real-time PCR". J. Clin. Microbiol. 47 (5): 1497–502. doi:10.1128/JCM.01868-08. PMC 2681835. PMID 19297596.
  4. ^ Tortoli, Enrico; Brown-Elliott, Barbara A.; Chalmers, James D.; Cirillo, Daniela M.; Daley, Charles L.; Emler, Stefan; Floto, R. Andres; Garcia, Maria J.; Hoefsloot, Wouter; Koh, Won-Jung; Lange, Christoph (2019-07-01). "Same meat, different gravy: Ignore the new names of mycobacteria". European Respiratory Journal. 54 (1). doi:10.1183/13993003.00795-2019. ISSN 0903-1936. PMID 31296783. S2CID 195893005.
  5. ^ Yamada, Hiroyuki; Chikamatsu, Kinuyo; Aono, Akio; Murata, Kazuyoshi; Miyazaki, Naoyuki; Kayama, Yoko; Bhatt, Apoorva; Fujiwara, Nagatoshi; Maeda, Shinji; Mitarai, Satoshi (2020). "Fundamental Cell Morphologies Examined With Cryo-TEM of the Species in the Novel Five Genera Robustly Correlate With New Classification in Family Mycobacteriaceae". Frontiers in Microbiology. 11: 562395. doi:10.3389/fmicb.2020.562395. ISSN 1664-302X. PMC 7701246. PMID 33304323.