Myelin regulatory factor

Myelin regulatory factor
Myelin regulatory factor
Identifiers
Symbol	MYRF
InterPro	IPR026933
Membranome	237

MYRF
Identifiers
Aliases	MYRF, C11orf9, MRF, Ndt80, pqn-47, myelin regulatory factor, 11orf9, MMERV, CUGS
External IDs	OMIM: 608329; MGI: 2684944; HomoloGene: 32167; GeneCards: MYRF; OMA:MYRF - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	61,788,518 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	10,218,112 bp
RNA expression pattern
	Top expressed in
	middle frontal gyrus; ; C1 segment; ; inferior ganglion of vagus nerve; ; inferior olivary nucleus; ; subthalamic nucleus; ; ventral tegmental area; ; external globus pallidus; ; superior vestibular nucleus; ; dorsal motor nucleus of vagus nerve; ; pars reticulata;
	Top expressed in
	pyloric antrum; ; epithelium of stomach; ; lumbar subsegment of spinal cord; ; mucous cell of stomach; ; motor neuron; ; yolk sac; ; abdominal wall; ; substantia nigra; ; optic nerve; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; hydrolase activity; DNA binding; DNA-binding transcription factor activity; identical protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	endoplasmic reticulum membrane; nucleus; membrane; cytoplasm; integral component of membrane; endoplasmic reticulum; nucleoplasm; Golgi apparatus; cytosol;
Biological process	positive regulation of myelination; oligodendrocyte differentiation; regulation of transcription, DNA-templated; proteolysis; central nervous system myelination; central nervous system myelin maintenance; cell differentiation; positive regulation of transcription, DNA-templated; transcription, DNA-templated; oligodendrocyte development; regulation of transcription by RNA polymerase II; protein autoprocessing;
	Sources:Amigo / QuickGO
Orthologs
	745
	225908
	ENSG00000124920
	ENSMUSG00000036098
	Q9Y2G1
	Q3UR85
	NM_001127392; NM_013279
	NM_001033481
	NP_001120864; NP_037411
	NP_001028653; NP_001391042
	Wikidata
View/Edit Human	View/Edit Mouse

Myelin regulatory factor (MyRF), also known as myelin gene regulatory factor (MRF), is a protein that in humans is encoded by the MYRF gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124920 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036098 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124920 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036098 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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