NFYC

NFYC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N1J, 4AWL, 4CSR
Identifiers
Aliases	NFYC, CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC, nuclear transcription factor Y subunit gamma
External IDs	OMIM: 605344; MGI: 107901; HomoloGene: 7440; GeneCards: NFYC; OMA:NFYC - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	40,771,603 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,688,769 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; apex of heart; ; muscle of thigh; ; monocyte; ; tendon of biceps brachii; ; right lobe of thyroid gland; ; right auricle; ; gastrocnemius muscle; ; ganglionic eminence; ; skin of abdomen;
	Top expressed in
	secondary oocyte; ; zygote; ; primary oocyte; ; genital tubercle; ; tail of embryo; ; thymus; ; heart; ; cerebellar cortex; ; bone marrow; ; olfactory bulb;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; transcription coactivator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription factor binding; sequence-specific DNA binding;
Cellular component	CCAAT-binding factor complex; protein-DNA complex; nucleus; nucleoplasm; RNA polymerase II transcription regulator complex;
Biological process	regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription by RNA polymerase II; protein folding; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; regulation of cholesterol biosynthetic process; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	4802
	18046
	ENSG00000066136
	ENSMUSG00000032897
	Q13952
	P70353
NM_001142587; NM_001142588; NM_001142589; NM_001142590; NM_001308114;
	NM_001308115; NM_014223
NM_001048168; NM_001277095; NM_008692; NM_001357192; NM_001357193;
	NM_001357194
NP_001136059; NP_001136060; NP_001136061; NP_001136062; NP_001295043;
	NP_001295044; NP_055038
NP_001041633; NP_001264024; NP_032718; NP_001344121; NP_001344122;
	NP_001344123
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear transcription factor Y subunit gamma is a protein that in humans is encoded by the NFYC gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000066136 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032897 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sinha S, Maity SN, Seldin MF, de Crombrugghe B (Feb 1997). "Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor". Genomics. 37 (2): 260–3. doi:10.1006/geno.1996.0555. PMID 8921405.
^ Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R (Aug 1997). "Cloning and expression of human NF-YC". Gene. 193 (1): 119–25. doi:10.1016/S0378-1119(97)00109-1. PMID 9249075.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000066136 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032897 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8921405-5] Sinha S, Maity SN, Seldin MF, de Crombrugghe B (Feb 1997). "Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor". Genomics. 37 (2): 260–3. doi:10.1006/geno.1996.0555. PMID 8921405.

[pmid9249075-6] Bellorini M, Zemzoumi K, Farina A, Berthelsen J, Piaggio G, Mantovani R (Aug 1997). "Cloning and expression of human NF-YC". Gene. 193 (1): 119–25. doi:10.1016/S0378-1119(97)00109-1. PMID 9249075.

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

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