NOX2

CYBB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX, cytochrome b-245 beta chain, CGDX
External IDsOMIM: 300481; MGI: 88574; HomoloGene: 68054; GeneCards: CYBB; OMA:CYBB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000397

NM_007807

RefSeq (protein)

NP_000388

NP_031833

Location (UCSC)Chr X: 37.78 – 37.81 MbChr X: 9.3 – 9.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NADPH oxidase 2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2 gene (also called CYBB gene).[5] The protein is a superoxide generating enzyme which forms reactive oxygen species (ROS).

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165168Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000015340Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CYBB cytochrome b-245, beta polypeptide (chronic granulomatous disease)".