NUBPL

NUBPL
Identifiers
Aliases	NUBPL, C14orf127, IND1, huInd1, nucleotide binding protein like, MC1DN21, NUBP iron-sulfur cluster assembly factor, mitochondrial
External IDs	OMIM: 613621; MGI: 1924076; HomoloGene: 11854; GeneCards: NUBPL; OMA:NUBPL - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	31,861,224 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	52,359,527 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; Skeletal muscle tissue of biceps brachii; ; testicle; ; bronchial epithelial cell; ; sural nerve; ; gonad; ; right auricle; ; left ventricle; ; lower lobe of lung; ; muscle of thigh;
	Top expressed in
	left ventricle; ; interventricular septum; ; spinal ganglia; ; peripheral nervous system; ; superior cervical ganglion; ; epiblast; ; proximal tubule; ; right kidney; ; ovary; ; upper arm;
	More reference expression data
	n/a
Gene ontology
Molecular function	4 iron, 4 sulfur cluster binding; nucleotide binding; iron-sulfur cluster binding; ATP binding; metal ion binding;
Cellular component	mitochondrial matrix; mitochondrion; plasma membrane;
Biological process	mitochondrion morphogenesis; mitochondrial respiratory chain complex I assembly; iron-sulfur cluster assembly;
	Sources:Amigo / QuickGO
Orthologs
	80224
	76826
	ENSG00000151413
	ENSMUSG00000035142
	Q8TB37
	Q9CWD8
	NM_001201573; NM_001201574; NM_025152
	NM_029760
	NP_001188502; NP_001188503; NP_079428
	NP_084036
	Wikidata
View/Edit Human	View/Edit Mouse

Iron-sulfur protein NUBPL (IND1) also known as nucleotide-binding protein-like (NUBPL), IND1 homolog, Nucleotide-binding protein-like or huInd1 is an iron-sulfur (Fe/S) protein that, in humans, is encoded by the NUBPL gene, located on chromosome 14q12. It has an early role in the assembly of the mitochondrial complex I assembly pathway.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000151413 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035142 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NUBPL nucleotide binding protein like [ Homo sapiens (human) ]". Retrieved 2018-07-27.
^ Cite error: The named reference uniprot was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000151413 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035142 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: NUBPL nucleotide binding protein like [ Homo sapiens (human) ]". Retrieved 2018-07-27.

[uniprot-6] Cite error: The named reference uniprot was invoked but never defined (see the help page).

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