NUDT15

NUDT15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5BON
Identifiers
Aliases	NUDT15, MTH2, NUDT15D, nudix hydrolase 15
External IDs	OMIM: 615792; MGI: 2443366; HomoloGene: 10109; GeneCards: NUDT15; OMA:NUDT15 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	48,047,221 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	73,785,682 bp
RNA expression pattern
	Top expressed in
	gonad; ; endothelial cell; ; mucosa of transverse colon; ; oocyte; ; rectum; ; secondary oocyte; ; mucosa of sigmoid colon; ; palpebral conjunctiva; ; gingival epithelium; ; endometrium;
	Top expressed in
	spermatocyte; ; muscle of thigh; ; morula; ; embryo; ; ventricular zone; ; embryo; ; tail of embryo; ; renal corpuscle; ; epiblast; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; hydrolase activity; metal ion binding; 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; nucleoside-diphosphatase activity; nucleotide diphosphatase activity; protein binding; NADH pyrophosphatase activity; nucleoside-triphosphate diphosphatase activity;
Cellular component	cytosol;
Biological process	nucleobase-containing small molecule catabolic process; dGTP catabolic process; mitotic cell cycle; purine nucleotide catabolic process; DNA protection; regulation of proteasomal protein catabolic process; nucleoside phosphate catabolic process; response to reactive oxygen species; purine deoxyribonucleoside triphosphate catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	55270
	214254
	ENSG00000136159
	ENSMUSG00000033405
	Q9NV35
	Q8BG93
	NM_018283; NM_001304745
	NM_172527; NM_001360484
	NP_001291674; NP_060753
	NP_766115; NP_001347413
	Wikidata
View/Edit Human	View/Edit Mouse

Nudix hydrolase 15 is a protein that in humans is encoded by the NUDT15 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136159 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033405 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Nudix hydrolase 15".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136159 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033405 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Nudix hydrolase 15".

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