NUDT9

NUDT9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Q33, 1QVJ
Identifiers
Aliases	NUDT9, NUDT10, nudix hydrolase 9
External IDs	OMIM: 606022; MGI: 1921417; HomoloGene: 11435; GeneCards: NUDT9; OMA:NUDT9 - orthologs
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	104,213,245 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; body of pancreas; ; middle temporal gyrus; ; duodenum; ; parotid gland; ; right adrenal gland; ; rectum; ; jejunal mucosa; ; left adrenal gland; ; glomerulus;
	Top expressed in
	saccule; ; otic placode; ; otic vesicle; ; vestibular membrane of cochlear duct; ; seminiferous tubule; ; fetal liver hematopoietic progenitor cell; ; sciatic nerve; ; interventricular septum; ; extensor digitorum longus muscle; ; plantaris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hydrolase activity; ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; adenosine-diphosphatase activity;
Cellular component	mitochondrial matrix; intracellular anatomical structure; extracellular exosome; mitochondrion; cell junction; nuclear membrane;
Biological process	nucleobase-containing small molecule catabolic process; IDP catabolic process; ADP catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	53343
	74167
	n/a
	ENSMUSG00000029310
	Q9BW91
	Q8BVU5
	NM_001248011; NM_024047; NM_198038
	NM_028794
	NP_001234940; NP_076952; NP_932155
	NP_083070
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribose pyrophosphatase, mitochondrial is an enzyme that in humans is encoded by the NUDT9 gene.^[4]^[5]^[6]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029310 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Perraud AL, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet JP, Scharenberg AM (May 2001). "ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology". Nature. 411 (6837): 595–9. Bibcode:2001Natur.411..595P. doi:10.1038/35079100. PMID 11385575. S2CID 4338852.
^ Perraud AL, Shen B, Dunn CA, Rippe K, Smith MK, Bessman MJ, Stoddard BL, Scharenberg AM (Jan 2003). "NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase". J Biol Chem. 278 (3): 1794–801. doi:10.1074/jbc.M205601200. PMID 12427752.
^ "Entrez Gene: NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9".