Neuromedin U receptor 2

NMUR2
Identifiers
Aliases	NMUR2, FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1, Neuromedin U receptor 2
External IDs	OMIM: 605108; MGI: 2441765; HomoloGene: 49618; GeneCards: NMUR2; OMA:NMUR2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	152,433,368 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	55,931,836 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; testicle; ; mucosa of ileum; ; deltoid muscle; ; corpus callosum; ; skin of thigh; ; C1 segment; ; internal globus pallidus; ; right testis; ; right lung;
	Top expressed in
	embryo; ; submandibular gland; ; cervix; ; jejunum; ; duodenum; ; skin of abdomen; ; trachea; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; signal transducer activity; neuromedin U binding; neuropeptide receptor activity; neuromedin U receptor activity; intracellular calcium activated chloride channel activity; GTP binding; G protein-coupled receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; intracellular anatomical structure;
Biological process	reduction of food intake in response to dietary excess; calcium ion transport; phospholipase C-activating G protein-coupled receptor signaling pathway; activation of phospholipase A2 activity; feeding behavior; inositol phosphate-mediated signaling; regulation of smooth muscle contraction; arachidonic acid secretion; positive regulation of cytosolic calcium ion concentration; cell-cell signaling; response to pain; calcium-mediated signaling; signal transduction; grooming behavior; central nervous system development; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; ion transmembrane transport; regulation of sensory perception of pain;
	Sources:Amigo / QuickGO
Orthologs
	56923
	216749
	ENSG00000132911
	ENSMUSG00000037393
	Q9GZQ4
	Q8BZ39
	NM_020167
	NM_153079
	NP_064552
	NP_694719
	Wikidata
View/Edit Human	View/Edit Mouse

Neuromedin-U receptor 2 is a protein that in humans is encoded by the NMUR2 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132911 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037393 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tate CG, Grisshammer R (Jan 1997). "Heterologous expression of G-protein-coupled receptors". Trends Biotechnol. 14 (11): 426–30. doi:10.1016/0167-7799(96)10059-7. PMID 8940772.
^ Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q (Jul 2000). "Identification of receptors for neuromedin U and its role in feeding". Nature. 406 (6791): 70–4. doi:10.1038/35017610. PMID 10894543. S2CID 205007370.
^ "Entrez Gene: NMUR2 neuromedin U receptor 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132911 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037393 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8940772-5] Tate CG, Grisshammer R (Jan 1997). "Heterologous expression of G-protein-coupled receptors". Trends Biotechnol. 14 (11): 426–30. doi:10.1016/0167-7799(96)10059-7. PMID 8940772.

[pmid10894543-6] Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q (Jul 2000). "Identification of receptors for neuromedin U and its role in feeding". Nature. 406 (6791): 70–4. doi:10.1038/35017610. PMID 10894543. S2CID 205007370.

[entrez-7] "Entrez Gene: NMUR2 neuromedin U receptor 2".

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