Neuropeptide Y receptor Y1

NPY1R
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F1U, 2IIL
Identifiers
Aliases	NPY1R, NPY1-R, NPYR, Neuropeptide Y receptor Y1
External IDs	OMIM: 162641; MGI: 104963; HomoloGene: 700; GeneCards: NPY1R; OMA:NPY1R - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	163,344,832 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	67,159,444 bp
RNA expression pattern
	Top expressed in
	spleen; ; popliteal artery; ; tibial arteries; ; right adrenal cortex; ; left adrenal cortex; ; Descending thoracic aorta; ; adipose tissue; ; germinal epithelium; ; superficial temporal artery; ; subcutaneous adipose tissue;
	Top expressed in
	ascending aorta; ; aortic valve; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; primary visual cortex; ; trigeminal ganglion; ; muscle of thigh; ; hippocampus proper; ; posterior horn of spinal cord; ; spinal ganglia;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide Y receptor activity; G protein-coupled receptor activity; signal transducer activity; protein binding; peptide YY receptor activity; pancreatic polypeptide receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane;
Biological process	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; locomotory behavior; regulation of multicellular organism growth; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; outflow tract morphogenesis; blood circulation; regulation of blood pressure; feeding behavior; glucose metabolic process; sensory perception of pain; neuropeptide signaling pathway; signal transduction; chemical synaptic transmission; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	4886
	18166
	ENSG00000164128
	ENSMUSG00000036437
	P25929
	Q04573
	NM_000909
	NM_010934; NM_001358955
	NP_000900
	NP_035064; NP_001345884
	Wikidata
View/Edit Human	View/Edit Mouse

Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164128 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036437 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Herzog H, Baumgartner M, Vivero C, Selbie LA, Auer B, Shine J (March 1993). "Genomic organization, localization, and allelic differences in the gene for the human neuropeptide Y Y1 receptor". The Journal of Biological Chemistry. 268 (9): 6703–7. doi:10.1016/S0021-9258(18)53306-8. PMID 8095935.
^ "Entrez Gene: NPY1R neuropeptide Y receptor Y1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164128 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036437 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8095935-5] Herzog H, Baumgartner M, Vivero C, Selbie LA, Auer B, Shine J (March 1993). "Genomic organization, localization, and allelic differences in the gene for the human neuropeptide Y Y1 receptor". The Journal of Biological Chemistry. 268 (9): 6703–7. doi:10.1016/S0021-9258(18)53306-8. PMID 8095935.

[entrez-6] "Entrez Gene: NPY1R neuropeptide Y receptor Y1".

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