Ngwane refers to a tribe that is part of the Nguni people. It may also refer to:
Between 1818 and 1828, Shaka's wars contributed to a series of forced migrations known as the Mfecane, Difaqane, Lifaqane, or Fetcani. During this period, groups of refugees fleeing Shaka's assaults—such as the Hlubi and Ngwane clans were followed later by the Mantatees and the Matabele under Mzilikazi and crossed the Drakensberg to the west, devastating other chiefdoms in their path.