| Nicomedes II | |
|---|---|
 | |
| King of Bithynia | |
| Reign | 149 – 127 BC |
| Predecessor | Prusias II |
| Successor | Nicomedes III |
| Born | Bithynia (modern-day Turkey) |
| Died | 127 BC Nicomedia (modern-day İzmit, Kocaeli, Turkey) |
| Issue | Nicomedes III Nysa |
| Greek | Νικομήδης Β΄ |
| Father | Prusias II |
| Mother | Apame IV |
| Religion | Greek Polytheism |
Nicomedes II Epiphanes (Greek: Νικομήδης ὁ Ἐπιφανής "Nicomedes God-Manifest") was the king of Bithynia from 149 to c. 127 BC. He was fourth in descent from Nicomedes I. Nicomedes II was the son and successor of Prusias II and Apame IV. His parents were related as they were maternal cousins.