An odontogenic infection is an infection that originates within a tooth or in the closely surrounding tissues.[1] The term is derived from odonto- (Ancient Greek: ὀδούς, odoús – 'tooth') and -genic (Ancient Greek: -γενής, -γενῶς; -genḗs, -genôs – 'birth'). The most common causes for odontogenic infection to be established are dental caries, deep fillings, failed root canal treatments, periodontal disease, and pericoronitis.[2] Odontogenic infection starts as localised infection and may remain localised to the region where it started, or spread into adjacent or distant areas.
It is estimated that 90–95% of all orofacial infections originate from the teeth or their supporting structures and are the most common infections in the oral and maxilofacial region.[3] Odontogenic infections can be severe if not treated and are associated with mortality rate of 10 to 40%.[4] Furthermore, about 70% of odontogenic infections occur as periapical inflammation, i.e. acute periapical periodontitis or a periapical abscess.[3] The next most common form of odontogenic infection is the periodontal abscess.[3] Despite being more common in underprivileged regions, odontogenic infections affect people from all over the world, even in developed countries. [5]