Ohtahara syndrome

Ohtahara syndrome[1]
Other namesEarly infantile epileptic encephalopathy with burst-suppression; Early Infantile Developmental & Epileptic Encephalopathy
SpecialtyNeurology Edit this on Wikidata

Ohtahara syndrome (OS), also known as Early Infantile Developmental & Epileptic Encephalopathy (EIDEE)[2] is a progressive epileptic encephalopathy. The syndrome is outwardly characterized by tonic spasms and partial seizures within the first few months of life,[3] and receives its more elaborate name from the pattern of burst activity on an electroencephalogram (EEG). It is an extremely debilitating progressive neurological disorder, involving intractable seizures and severe intellectual disabilities. No single cause has been identified, although in many cases structural brain damage is present.[4]

  1. ^ Berg AT, Berkovic SF, Brodie MJ, et al. (April 2010). "Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009". Epilepsia. 51 (4): 676–85. doi:10.1111/j.1528-1167.2010.02522.x. PMID 20196795.
  2. ^ "Ohtahara Syndrome". Epilepsy Foundation. Retrieved 2019-12-13.
  3. ^ "OHTAHARA SYNDROME". www.epilepsydiagnosis.org. Retrieved 2019-12-13.
  4. ^ National Institute of Neurological Disorders and Stroke (5 December 2008). "NINDS Ohtahara Syndrome Information Page". Archived from the original on 28 February 2009. Retrieved 2009-03-10.