OpenPHACTS

Open PHACTS
Formation2011
TypePublic–private partnership
PurposeSemantic interoperability for drug discovery through Open innovation
Membership
27 member organisations
Key people
Website

Open PHACTS (Open Pharmacological Concept Triple Store) was a European initiative public–private partnership between academia, publishers, enterprises, pharmaceutical companies and other organisations working to enable better, cheaper and faster drug discovery.[1][2][3][4] It has been funded by the Innovative Medicines Initiative,[5] selected as part of three projects to "design methods for common standards and sharing of data for more efficient drug development and patient treatment in the future".[6][7]

  1. ^ Williams, A. J.; Harland, L.; Groth, P.; Pettifer, S.; Chichester, C.; Willighagen, E. L.; Evelo, C. T.; Blomberg, N.; Ecker, G.; Goble, C.; Mons, B. (2012). "Open PHACTS: Semantic interoperability for drug discovery". Drug Discovery Today. 17 (21–22): 1188–1198. doi:10.1016/j.drudis.2012.05.016. PMID 22683805.
  2. ^ Ecker, G. F.; Williams-Jones, B. (2012). "Open Innovation in Drug Discovery". Molecular Informatics. 31 (8): 519–520. doi:10.1002/minf.201280004. PMID 27477598.
  3. ^ Gray, Alasdair J.G.; Groth, Paul; Loizou, Antonis; Askjaer, Sune; Brenninkmeijer, Christian; Burger, Kees; Chichester, Christine; Evelo, Chris T.; Goble, Carole; Harland, Lee; Pettifer, Steve; Thompson, Mark; Waagmeester, Andra; Williams, Antony John (2014). "Applying linked data approaches to pharmacology: Architectural decisions and implementation". Semantic Web. 5 (2): 101–113. arXiv:1005.2643. doi:10.3233/SW-2012-0088.
  4. ^ Ciccarese, P; Soiland-Reyes, S; Belhajjame, K; Gray, A. J.; Goble, C; Clark, T (2013). "PAV ontology: Provenance, authoring and versioning". Journal of Biomedical Semantics. 4 (1): 37. arXiv:1304.7224. doi:10.1186/2041-1480-4-37. PMC 4177195. PMID 24267948.
  5. ^ "Open PHACTS at IMI - The Innovative Medicines Initiative".
  6. ^ Watson, R. (2011). "Europe provides €172m for research into innovative medicines". BMJ. 342: d1577. doi:10.1136/bmj.d1577. PMID 21393337. S2CID 40608990.
  7. ^ Goble, C.; Gray, A. J. G.; Harland, L.; Karapetyan, K.; Loizou, A.; Mikhailov, I.; Rankka, Y. N.; Senger, S.; Tkachenko, V.; Williams, A. J.; Willighagen, E. L. (2013). "Incorporating Commercial and Private Data into an Open Linked Data Platform for Drug Discovery". Advanced Information Systems Engineering. Lecture Notes in Computer Science. Vol. 8219. pp. 65–80. doi:10.1007/978-3-642-41338-4_5. ISBN 978-3-642-41337-7.