Optic disc drusen

Optic disc drusen
Other namesOptic nerve head drusen
Bilateral optic disc drusen in computed tomography seen as dense spots at the optical disc
SpecialtyNeurology Edit this on Wikidata

Optic disc drusen (ODD) are globules of mucoproteins and mucopolysaccharides that progressively calcify in the optic disc.[1][2] They are thought to be the remnants of the axonal transport system of degenerated retinal ganglion cells.[3][4][5] ODD have also been referred to as congenitally elevated or anomalous discs, pseudopapilledema, pseudoneuritis, buried disc drusen, and disc hyaline bodies.[6]

  1. ^ Golnik, K. (2006). Congenital anomalies and acquired abnormalities of the optic nerve, (Version 14.3). UptoDate (On-Line Serial)
  2. ^ Friedman AH, Henkind P, Gartner S (April 1975). "Drusen of the optic disc. A histopathological study". Trans Ophthalmol Soc U K. 95 (1): 4–9. PMID 1064209.
  3. ^ Rosen E, Almog Y, Assia E (November 2005). "[Optic disc drusen and acute vision loss]". Harefuah (in Hebrew). 144 (11): 785–89, 822. PMID 16358654.
  4. ^ Tso MO (October 1981). "Pathology and pathogenesis of drusen of the optic nervehead". Ophthalmology. 88 (10): 1066–80. doi:10.1016/s0161-6420(81)80038-3. PMID 7335311.
  5. ^ Kapur R, Pulido JS, Abraham JL, Sharma M, Buerk B, Edward DP (January 2008). "Histologic findings after surgical excision of optic nerve head drusen". Retina. 28 (1): 143–46. doi:10.1097/IAE.0b013e31815e98d8. PMID 18185151. S2CID 21285492.
  6. ^ "Optic Nerve Head Drusen". Handbook of Ocular Disease Management. Jobson Publishing L.L.C. 2001. Archived from the original on 2004-12-09.