Oral mucosa

Oral mucosa
Details
Identifiers
Latintunica mucosa oris
MeSHD009061
TA98A05.1.01.002
TA22785
FMA59660
Anatomical terminology

The oral mucosa is the mucous membrane lining the inside of the mouth. It comprises stratified squamous epithelium, termed "oral epithelium", and an underlying connective tissue termed lamina propria.[1] The oral cavity has sometimes been described as a mirror that reflects the health of the individual.[2] Changes indicative of disease are seen as alterations in the oral mucosa lining the mouth, which can reveal systemic conditions, such as diabetes or vitamin deficiency, or the local effects of chronic tobacco or alcohol use.[3] The oral mucosa tends to heal faster and with less scar formation compared to the skin.[4] The underlying mechanism remains unknown, but research suggests that extracellular vesicles might be involved.[5]

  1. ^ Nanci (2013). Ten Cate's Oral Histology. Elsevier. p. 280.
  2. ^ Oral Manifestations of Systemic Diseases at eMedicine
  3. ^ Squier, Christopher A.; Kremer, Mary J. (2001). "Biology of Oral Mucosa and Esophagus". Journal of the National Cancer Institute. Monographs. 2001 (29): 7–15. doi:10.1093/oxfordjournals.jncimonographs.a003443. PMID 11694559.
  4. ^ Mak, Karen (2009). "Scarless healing of oral mucosa is characterized by faster resolution of inflammation and control of myofibroblast action compared to skin wounds in the red Duroc pig model". Journal of Dermatological Science. 56 (3): 168–180. doi:10.1016/j.jdermsci.2009.09.005. PMID 19854029.
  5. ^ Sjöqvist, Sebastian (2019). "Exosomes derived from clinical-grade oral mucosal epithelial cell sheets promote wound healing". Journal of Extracellular Vesicles. 8 (1): 1565264. doi:10.1080/20013078.2019.1565264. PMC 6346716. PMID 30719240.