Orient House (Arabic: بيت الشرق bayt ʾal-šarq, Hebrew: האוריינט האוס) is a building located in Jerusalem that served as the headquarters of the Palestine Liberation Organization (PLO) in the 1980s and 1990s.
Built in 1897 by Ismail Musa Al-Husseini, it has been owned by the Al-Husseini family since. Originally intended to serve as a family residence, it was at times vacated to host important guests, such as Kaiser Wilhelm II of Germany in 1898 and Emperor Haile Selassie of Ethiopia in 1936.