 | This article includes a list of general references, but it lacks sufficient corresponding inline citations. (March 2011) |
| Osteoid | |
|---|---|
 | |
| Identifiers | |
| FMA | 66830 |
| Anatomical terminology | |
In histology, osteoid is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue.[1] Osteoblasts begin the process of forming bone tissue by secreting the osteoid as several specific proteins. The osteoid and its adjacent bone cells have developed into new bone tissue when it becomes mineralized.
Osteoid makes up about fifty percent of bone volume and forty percent of bone weight. It is composed of fibers and ground substance. The predominant type of fiber is type I collagen and comprises ninety percent of the osteoid. The ground substance is mostly made up of chondroitin sulfate and osteocalcin.
- ^ Trammell, Lindsay H.; Kroman, Anne M. (2013-01-01), DiGangi, Elizabeth A.; Moore, Megan K. (eds.), "Chapter 13 - Bone and Dental Histology", Research Methods in Human Skeletal Biology, Academic Press, pp. 361–395, doi:10.1016/b978-0-12-385189-5.00013-3, ISBN 978-0-12-385189-5, retrieved 2020-11-18