Oxybuprocaine

Oxybuprocaine
Clinical data
Trade names	Novesin(e)
AHFS/Drugs.com	International Drug Names
Pregnancy; category	AU: D; ;
Routes of; administration	Topical
ATC code	D04AB03 (WHO) S01HA02 (WHO);
Legal status
Legal status	BR: Class C1 (Other controlled substances);
Pharmacokinetic data
Metabolism	Esterases in blood plasma and liver
Identifiers
	IUPAC name 2-diethylaminoethyl 4-amino-3-butoxy-benzoate;
CAS Number	99-43-4 ;
PubChem CID	4633;
IUPHAR/BPS	7123;
DrugBank	DB00892 ;
ChemSpider	4472 ;
UNII	AXQ0JYM303;
KEGG	D08319 ;
ChEBI	CHEBI:309594 ;
ChEMBL	ChEMBL1200 ;
CompTox Dashboard (EPA)	DTXSID7048530 ;
Chemical and physical data
Formula	C17H28N2O3
Molar mass	308.422 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCCN(CC)CC)c1cc(OCCCC)c(cc1)N;
	InChI InChI=1S/C17H28N2O3/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3/h8-9,13H,4-7,10-12,18H2,1-3H3 ; Key:CMHHMUWAYWTMGS-UHFFFAOYSA-N ;
	(verify)

Oxybuprocaine (INN), also known as benoxinate or BNX, is an ester-type local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine is sold by Novartis under the brand names Novesine or Novesin.

Safety for use in pregnancy and lactation has not been established.

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

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