| Combination of | |
|---|---|
| Oxycodone | Opioid analgesic |
| Aspirin | Non-steroidal anti-inflammatory drug |
| Clinical data | |
| Trade names | Percodan |
| AHFS/Drugs.com | percodan |
| License data | |
| Routes of administration | Oral |
| ATC code | |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | |
| KEGG | |
 | This article needs additional citations for verification. (June 2022) |
Oxycodone/aspirin (trade name Percodan) is a combination drug marketed by Endo Pharmaceuticals. It is a tablet containing a mixture of 325 mg (5 grains) of aspirin and 4.8355 mg of oxycodone HCl (equivalent to 4.3346 mg of oxycodone as the free base); it is an opioid/non-opioid combination used to treat moderate to moderately severe pain.[1] The safety of the combination during pregnancy has not been established, although aspirin is generally contraindicated during pregnancy, and the drug has been placed in pregnancy category D.[2] Inactive ingredients include D&C Yellow 10, FD&C Yellow 6, microcrystalline cellulose, and corn starch.[2] Percodan was first marketed by DuPont Pharmaceuticals and prescribed in the United States in 1950. Once a widely prescribed painkiller, it has largely been replaced by alternative oxycodone compounds containing paracetamol (acetaminophen) instead of aspirin, such as Percocet.
- ^ "Percodan Package Insert" (PDF). Endo Pharmaceuticals. July 2010. Archived from the original (PDF) on 14 May 2016. Retrieved 4 December 2012.
- ^ a b "PERCODAN - oxycodone hydrochloride and aspirin tablet". DailyMed. United States National Library of Medicine. April 2009. Retrieved 10 January 2011.