PAFAH1B3

PAFAH1B3
Identifiers
Aliases	PAFAH1B3, PAFAHG, platelet activating factor acetylhydrolase 1b catalytic subunit 3
External IDs	OMIM: 603074; MGI: 108414; HomoloGene: 1933; GeneCards: PAFAH1B3; OMA:PAFAH1B3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	42,303,546 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	24,997,411 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; gonad; ; right hemisphere of cerebellum; ; mucosa of transverse colon; ; nucleus accumbens; ; testicle; ; prefrontal cortex; ; right adrenal gland; ; amygdala;
	Top expressed in
	medial ganglionic eminence; ; neural tube; ; ventricular zone; ; maxillary prominence; ; mandibular prominence; ; human fetus; ; efferent ductule; ; hand; ; abdominal wall; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	1-alkyl-2-acetylglycerophosphocholine esterase activity; platelet-activating factor acetyltransferase activity; protein binding; hydrolase activity; identical protein binding; protein heterodimerization activity; phospholipase A2 activity;
Cellular component	cytoplasm; extracellular exosome; membrane; cytosol;
Biological process	lipid catabolic process; brain development; spermatogenesis; nervous system development; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	5050
	18476
	ENSG00000079462
	ENSMUSG00000005447
	Q15102
	Q61205
	NM_002573; NM_001145939; NM_001145940
	NM_008776; NM_001357350
	NP_001139411; NP_001139412; NP_002564
	NP_032802; NP_001344279
	Wikidata
View/Edit Human	View/Edit Mouse

Platelet-activating factor acetylhydrolase IB subunit gamma is an enzyme that in humans is encoded by the PAFAH1B3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000079462 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000005447 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Adachi H, Tsujimoto M, Hattori M, Arai H, Inoue K (Sep 1995). "cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues". Biochemical and Biophysical Research Communications. 214 (1): 180–7. doi:10.1006/bbrc.1995.2272. PMID 7669037.
^ "Entrez Gene: PAFAH1B3 platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000079462 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000005447 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7669037-5] Adachi H, Tsujimoto M, Hattori M, Arai H, Inoue K (Sep 1995). "cDNA cloning of human cytosolic platelet-activating factor acetylhydrolase gamma-subunit and its mRNA expression in human tissues". Biochemical and Biophysical Research Communications. 214 (1): 180–7. doi:10.1006/bbrc.1995.2272. PMID 7669037.

[entrez-6] "Entrez Gene: PAFAH1B3 platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa".

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