PBX3

PBX3
Identifiers
Aliases	PBX3, PBX homeobox 3
External IDs	OMIM: 176312; MGI: 97496; HomoloGene: 21243; GeneCards: PBX3; OMA:PBX3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	125,967,377 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	34,263,154 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right adrenal cortex; ; right ovary; ; left adrenal cortex; ; muscle layer of sigmoid colon; ; right auricle; ; internal globus pallidus; ; C1 segment; ; gallbladder; ; vena cava;
	Top expressed in
	Rostral migratory stream; ; epithelium of lens; ; substantia nigra; ; olfactory bulb; ; dorsal striatum; ; ciliary body; ; retinal pigment epithelium; ; dorsal tegmental nucleus; ; adrenal gland; ; external carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding;
Cellular component	nucleus; transcription regulator complex;
Biological process	regulation of respiratory gaseous exchange by nervous system process; adult locomotory behavior; anterior compartment pattern formation; dorsal spinal cord development; neuron development; regulation of transcription, DNA-templated; transcription by RNA polymerase II; posterior compartment specification; respiratory gaseous exchange by respiratory system; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	5090
	18516
	ENSG00000167081
	ENSMUSG00000038718
	P40426; Q96AL5
	O35317
	NM_001134778; NM_006195; NM_001330782
	NM_001290576; NM_016768
	NP_001128250; NP_001317711; NP_006186; NP_006186.1
	NP_001277505; NP_058048
	Wikidata
View/Edit Human	View/Edit Mouse

Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the PBX3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167081 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038718 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Monica K, Galili N, Nourse J, Saltman D, Cleary ML (Dec 1991). "PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1". Mol Cell Biol. 11 (12): 6149–57. doi:10.1128/mcb.11.12.6149. PMC 361792. PMID 1682799.
^ "Entrez Gene: PBX3 pre-B-cell leukemia homeobox 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167081 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038718 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1682799-5] Monica K, Galili N, Nourse J, Saltman D, Cleary ML (Dec 1991). "PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1". Mol Cell Biol. 11 (12): 6149–57. doi:10.1128/mcb.11.12.6149. PMC 361792. PMID 1682799.

[entrez-6] "Entrez Gene: PBX3 pre-B-cell leukemia homeobox 3".

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