PLCG1

PLCG1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1, phospholipase C gamma 1
External IDsOMIM: 172420; MGI: 97615; HomoloGene: 1997; GeneCards: PLCG1; OMA:PLCG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002660
NM_182811

NM_021280

RefSeq (protein)

NP_002651
NP_877963

NP_067255

Location (UCSC)Chr 20: 41.14 – 41.2 MbChr 2: 160.57 – 160.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phospholipase C, gamma 1, also known as PLCG1 and PLCgamma1, is a protein that in humans involved in cell growth, migration, apoptosis, and proliferation. It is encoded by the PLCG1 gene[5][6] and is part of the PLC superfamily.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124181Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016933Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bristol A, Hall SM, Kriz RW, Stahl ML, Fan YS, Byers MG, Eddy RL, Shows TB, Knopf JL (1988). "Phospholipase C-148: chromosomal location and deletion mapping of functional domains". Cold Spring Harbor Symposia on Quantitative Biology. 53 (2): 915–20. doi:10.1101/sqb.1988.053.01.105. PMID 3254788.
  6. ^ Burgess WH, Dionne CA, Kaplow J, Mudd R, Friesel R, Zilberstein A, Schlessinger J, Jaye M (September 1990). "Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase". Molecular and Cellular Biology. 10 (9): 4770–7. doi:10.1128/mcb.10.9.4770. PMC 361079. PMID 2167438.